HIV infection is associated with thoracic and abdominal aortic aneurysms: a prospective matched cohort study.
Julie HøghMichael Huy Cuong PhamAndreas Delhbaek KnudsenRebekka Faber ThudiumMarco GelpiPer Ejlstrup SigvardsenAndreas FuchsJørgen Tobias KühlShoaib AfzalBørge Grønne NordestgaardThomas Lars BenfieldLars Valeur KøberJan GerstoftKlaus Fuglsang KofoedSusanne Dam NielsenPublished in: European heart journal (2021)
PLWH had four-fold higher odds of aortic aneurysms compared to uninfected controls, and HIV status was independently associated with aortic aneurysms. Among PLWH, age, obesity and hepatitis B co-infection were associated with higher odds of aortic aneurysms. Our findings suggest that increased attention to aortic aneurysms in PLWH may be beneficial.
Keyphrases
- aortic valve
- left ventricular
- pulmonary artery
- antiretroviral therapy
- hiv infected
- aortic dissection
- abdominal aortic
- metabolic syndrome
- human immunodeficiency virus
- insulin resistance
- hepatitis c virus
- weight loss
- spinal cord
- heart failure
- hiv aids
- pulmonary hypertension
- adipose tissue
- weight gain
- high fat diet induced