Numerous Brugada syndrome-associated genetic variants have no effect on J-point elevation, syncope susceptibility, malignant cardiac arrhythmia, and all-cause mortality.

Jonas GhouseChristian Theil HaveMorten W SkovLaura AndreasenGustav Ahlberg Jonas Bille NielsenTea SkaabySøren-Peter OlesenNiels Grarup Allan LinnebergOluf PedersenHenrik VestergaardStig HaunsøJesper H SvendsenTorben HansenJørgen Kim KantersMorten S Olesen

Published in: Genetics in medicine : official journal of the American College of Medical Genetics (2016)

Our data indicate that a significant number of BrS-associated variants are not the monogenic cause of BrS.Genet Med advance online publication 06 October 2016.

Keyphrases

pulmonary embolism
copy number
electronic health record
social media
health information
big data
case report
healthcare
gene expression
dna methylation