Modification of the Polymer of a Bone Cement with Biodegradable Microspheres of PLGA and Loading with Daptomycin and Vancomycin Improve the Response to Bone Tissue Infection.

Joaquin García-GarcíaGalo AzuaraOscar Fraile-Martínez Cielo Garcia-MonteroMiguel Angel Álvarez-MonSara Ruíz-DíezMelchor Alvarez De Mon Julia Buján Natalio Garcia-Honduvilla Miguel Ángel OrtegaBasilio De la Torre

Published in: Polymers (2022)

bone cement with PLGA microspheres and its doping with the antibiotic daptomycin in combination with vancomycin improve the tissue response to bone infection.

Keyphrases

bone regeneration
bone mineral density
methicillin resistant staphylococcus aureus
drug delivery
soft tissue
bone loss
drug release
mass spectrometry
simultaneous determination
liquid chromatography