Moderate-Intensity Physical Exercise Protects Against Experimental 6-Hydroxydopamine-Induced Hemiparkinsonism Through Nrf2-Antioxidant Response Element Pathway.

Aderbal Silva Aguiar JuniorMarcelo DuzzioniAline Pertile RemorFabrine Sales Massafera TristãoFilipe C MatheusRita Raisman-VozariAlexandra LatiniRui Daniel Prediger

Published in: Neurochemical research (2015)

In mice, exercise activated Nrf2-ARE signaling in the nigrostriatal pathway that was protective against the development of hemiparkinsonism.

Keyphrases

high intensity
oxidative stress
diabetic rats
physical activity
type diabetes
drug induced
metabolic syndrome