Magnetic susceptibility in the deep gray matter may be modulated by apolipoprotein E4 and age with regional predilections: a quantitative susceptibility mapping study.
Younghee YimJong Duck ChoiJun Heong ChoYeonsil MoonSeol-Heui HanWon Jin MoonPublished in: Neuroradiology (2022)
Our study demonstrates that magnetic susceptibility in globus pallidus is related to APOE4 status while those of caudate and putamen are related to other factors including age. It suggests that brain iron accumulation in the deep gray matter is modulated by APOE4 and age with differential regional predilection.