SARS-CoV-2 mRNA Vaccination and Graves' Disease: A Report of 12 Cases and Review of the Literature.

Ying Jie CheeHuiling LiewWai Han HoiYingshan LeeBrenda LimHan Xin ChinRay Tian Rui LaiYunqing KohMichelle ThamCherng Jye SeowZhi Han QuekAbel Weiliang ChenTimothy Peng Lim QuekAlvin Wai Kit TanRinkoo Dalan

Published in: The Journal of clinical endocrinology and metabolism (2022)

Our case series provides insight into the characteristics of individuals in whom Graves' disease was triggered by the SARS-CoV-2 vaccination. Clinicians need to be vigilant of precipitation or exacerbation of autoimmune thyroid disorders in predisposed individuals after exposure to the SARS-CoV-2 vaccination. Further epidemiological and mechanistic studies are required to elucidate the possible associations between the SARS-CoV-2 vaccines and the development of thyroid autoimmunity.

Keyphrases

sars cov
respiratory syndrome coronavirus
palliative care
intensive care unit
binding protein