Association of Pharmacologic Treatment of Depression/Anxiety With Initial Patient-Reported Outcome Measures in Patients With Hip and Knee Osteoarthritis.

Alexander Rashad FaridAdriana P LiimakkaEmily B ParkerJeremy T SmithChristopher M MelnicAntonia F ChenJeffrey K Lange

Published in: The Journal of the American Academy of Orthopaedic Surgeons (2024)

:Our results indicate that pharmacologic treatment of depression/anxiety is associated with improved psychological health but not with improved physical symptoms related to OA. We observed a nonsignificant trend that patients with depression/anxiety who warrant pharmacologic treatment tend to have worse physical symptoms than those who do not; however, unadjusted analyses suggest this is a complex relationship beyond the isolated effect of pharmacologic treatment.

Keyphrases

sleep quality
mental health
physical activity
public health
combination therapy
patient reported outcomes
drug induced
health promotion