Decreased Platelet Inhibition by Thienopyridines in Hyperuricemia.

Silvia LeePatricia P WadowskiTimothy HoberstorferConstantin WeikertJoseph PultarChristoph W KoppSimon PanzerThomas Gremmel

Published in: Cardiovascular drugs and therapy (2020)

Hyperuricemia is associated with decreased platelet inhibition by thienopyridines but a normal response to ticagrelor. It remains to be established if lowering uric acid increases the antiplatelet effects of clopidogrel and prasugrel in hyperuricemic patients with HRPR.

Keyphrases

uric acid
percutaneous coronary intervention
metabolic syndrome
acute coronary syndrome
antiplatelet therapy
st segment elevation myocardial infarction
st elevation myocardial infarction
coronary artery disease
atrial fibrillation