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Crystal structure and Hirshfeld surface analysis of N-(tert-but-yl)-2-(phenyl-ethyn-yl)imidazo[1,2-a]pyridin-3-amine.

Zahira TberSevgi KansizMohamed El HafiMohammed LoubidiJabrane JouhaNecmi DegeEl Mokhtar EssassiJoel T Mague
Published in: Acta crystallographica. Section E, Crystallographic communications (2019)
The bicyclic imidazo[1,2-a]pyridine core of the title compound, C19H19N3, is relatively planar with an r.m.s. deviation of 0.040 Å. The phenyl ring is inclined to the mean plane of the imidazo[1,2-a]pyridine unit by 18.2 (1)°. In the crystal, mol-ecules are linked by N-H⋯H hydrogen bonds, forming chains along the c-axis direction. The chains are linked by C-H⋯π inter-actions, forming slabs parallel to the ac plane. The Hirshfeld surface analysis and fingerprint plots reveal that the crystal structure is dominated by H⋯H (54%) and C⋯H/H⋯C (35.6%) contacts. The crystal studied was refined as an inversion twin.
Keyphrases
  • crystal structure
  • solid state
  • single cell
  • gene expression
  • magnetic resonance imaging
  • contrast enhanced
  • quality control