When to Perform a Colonoscopy in Diverticular Disease and Why: A Personalized Approach.
Antonio TursiValerio PapaLoris Riccardo LopetusoLorenzo Maria VetroneAntonio GasbarriniAlfredo PapaPublished in: Journal of personalized medicine (2022)
Colonoscopy is a crucial diagnostic tool in managing diverticular disease (DD). Diverticulosis can often be an unexpected diagnosis when colonoscopy is performed in asymptomatic subjects, generally for colorectal cancer screening, or it could reveal an endoscopic picture compatible with DD, including acute diverticulitis, in patients suffering from abdominal pain or rectal bleeding. However, alongside its role in the differential diagnosis of colonic diseases, particularly with colon cancer after an episode of acute diverticulitis or segmental colitis associated with diverticulosis, the most promising use of colonoscopy in patients with DD is represented by its prognostic role when the DICA (Diverticular Inflammation and Complication Assessment) classification is applied. Finally, colonoscopy plays a crucial role in managing diverticular bleeding, and it could sometimes be used to resolve other complications, particularly as a bridge to surgery. This article aims to summarize "when" to safely perform a colonoscopy in the different DD settings and "why".
Keyphrases
- colorectal cancer screening
- liver failure
- end stage renal disease
- abdominal pain
- oxidative stress
- chronic kidney disease
- machine learning
- respiratory failure
- newly diagnosed
- minimally invasive
- ejection fraction
- drug induced
- deep learning
- peritoneal dialysis
- genome wide
- dna methylation
- hepatitis b virus
- gene expression
- single cell
- percutaneous coronary intervention
- endoscopic submucosal dissection