Regulating Hydrogenation Chemoselectivity of α,β-Unsaturated Aldehydes by Combination of Transfer and Catalytic Hydrogenation.
Yangyang ZhouZihao LiYanbo LiuJia HuoChen ChenQiling LiSongyang NiuShuangyin WangPublished in: ChemSusChem (2020)
Two hydrogenation mechanisms, transfer and catalytic hydrogenation, were combined to achieve higher regulation of hydrogenation chemoselectivity of cinnamyl aldehydes. Transfer hydrogenation with ammonia borane exclusively reduced C=O bonds to get cinnamyl alcohol, and Pt-loaded metal-organic layers efficiently hydrogenated C=C bonds to synthesize phenyl propanol with almost 100 % conversion rate. The hydrogenation could be performed under mild conditions without external high-pressure hydrogen and was applicable to various α,β-unsaturated aldehydes.