Clinical Response of Live-Attenuated, Listeria monocytogenes Expressing Mesothelin (CRS-207) with Chemotherapy in Patients with Malignant Pleural Mesothelioma.
Raffit HassanEvan AlleyHedy KindlerScott AntoniaThierry JahanSomayeh HonarmandNitya NairChan C WhitingAmanda EnstromEd LemmensTakahiro TsujikawaSushil KumarGina ChoeAnish ThomasKatherine McDougallAimee L MurphyElizabeth JaffeeLisa M CoussensDirk G BrockstedtPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2019)
Combination of CRS-207 and chemotherapy induced significant changes in the local tumor microenvironment and objective tumor responses in a majority of treated patients.