A miniature laser ablation probe relying on an optical fiber to deliver light requires a high coupling efficiency objective with sufficient magnification in order to provide adequate power and field for surgery. A diffraction-limited optical design is presented that utilizes high refractive index zinc sulfide to meet specifications while reducing the miniature objective down to two lenses. The design has a hypercentric conjugate plane on the fiber side and is telecentric on the tissue end. Two versions of the objective were built on a diamond lathe-a traditional cylindrical design and a custom-tapered mount. Both received an antireflective coating. The objectives performed as designed in terms of observable resolution and field of view as measured by imaging a 1951 USAF resolution target. The slanted edge technique was used to find Strehl ratios of 0.75 and 0.78, respectively, indicating nearly diffraction-limited performance. Finally, preliminary ablation experiments indicated threshold fluence of gold film was comparable to similar reported probes.
Keyphrases
- high resolution
- minimally invasive
- high speed
- cataract surgery
- single molecule
- coronary artery bypass
- small molecule
- room temperature
- crystal structure
- radiofrequency ablation
- fluorescence imaging
- quantum dots
- cancer therapy
- percutaneous coronary intervention
- coronary artery disease
- photodynamic therapy
- tissue engineering
- nucleic acid