Diterpene Ginkgolides Exert an Antidepressant Effect Through the NT3-TrkA and Ras-MAPK Pathways.

Ting WangShunjie BaiWei WangZhi ChenJian-Jun ChenZihong LiangXunzhong QiHailan ShenPeng Xie

Published in: Drug design, development and therapy (2020)

These findings provide novel insight into the mechanisms underlying the antidepressant action of DG, and should help advance the development of new therapeutic strategies for depression.

Keyphrases

major depressive disorder
signaling pathway
depressive symptoms
oxidative stress
bipolar disorder
wild type