Predictors of large cell transformation in patients with Sezary Syndrome-A retrospective analysis.

Neil K JairathRedina BardhiJohn S RungeRamona BledeaRuple JairathYang WangMatthew PatrickRyan A WilcoxAlexandra C HristovLam C TsoiTrilokraj Tejasvi

Published in: PloS one (2022)

Maximum TBSA involvement, peak LDH, presence of ulceration, and decreased levels of CD8+ cells in the peripheral blood may predict the development of LCT in patients with SS.

Keyphrases

peripheral blood
induced apoptosis
cell cycle arrest
single cell
cell therapy
endoplasmic reticulum stress
case report
oxidative stress
signaling pathway