Prognostic impact of germline BRCA1/2 pathogenic variants in breast cancer.

Giovanni CorsoAntonia GirardiMariarosaria CalvelloSara GandiniAurora GaetaMonica MarabelliFrancesca MagnoniPaolo VeronesiAliana Guerrieri-GonzagaBernardo Bonanni

Published in: Breast cancer research and treatment (2022)

Having been found to be associated with a lower risk of BC reappearance, germline BRCA1/2 PVs of the missense/splicing subtypes can be used as prognostic predictors and are likely to improve BC patients' management.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
dna repair
chronic kidney disease
breast cancer risk
prognostic factors
peritoneal dialysis
intellectual disability
patient reported