Insights from a computational analysis of the SARS-CoV-2 Omicron variant: Host-pathogen interaction, pathogenicity, and possible drug therapeutics.

Md Sorwer Alam ParvezManash Kumar SahaMd IbrahimYusha ArafMd Taufiqul IslamGen OhtsukiMohammad Jakir Hosen

Published in: Immunity, inflammation and disease (2022)

Omicron variant may be originated from the highly infectious B.1.620 variant, while it was less pathogenic due to the mutations in the prominent proteins. Nirmatrelvir, 13b, and Lopinavir would be the most effective, compared to other promising drugs that were proven effective.

Keyphrases

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coronavirus disease