Development of new brain metastases in triple negative breast cancer.

Ravi MedikondaSiddhartha SrivastavaTimothy KimYuanxuan XiaJennifer KimChristopher JacksonJon WeingartDebraj MukherjeeChetan BettegowdaGary GalliaHenry BremKristin RedmondVered StearnsLawrence KleinbergMichael Lim

Published in: Journal of neuro-oncology (2021)

Our findings highlight the highly aggressive intracranial nature of TNBC. The rate of new brain metastasis formation is higher in TNBC patients compared to non-TNBC patients. Furthermore, there is no survival benefit for WBRT in TNBC patients. These findings are relevant for clinicians planning brain radiation for TNBC patients as they may find more brain metastases at the time of brain radiation than they anticipated based on initial brain imaging.

Keyphrases

end stage renal disease
chronic kidney disease
small cell lung cancer
peritoneal dialysis
prognostic factors
radiation therapy
high resolution
patient reported outcomes
palliative care
resting state
functional connectivity
brain injury
radiation induced
optical coherence tomography