An iodine-containing probe as a tool for molecular detection in secondary ion mass spectrometry.
Selda KabatasPaola Agüi-GonzalezShama Sograte-IdrissiSebastian JähneFelipe OpazoNhu T N PhanSilvio O RizzoliPublished in: Chemical communications (Cambridge, England) (2022)
We developed here an iodine-containing probe that can be used to identify the molecules of interest in secondary ion mass spectrometry (SIMS) by simple immunolabelling procedures. The immunolabelled iodine probe was readily combined with previously-developed SIMS probes carrying fluorine, to generate dual-channel SIMS data. This probe should provide a useful complement to the currently available SIMS probes, thus expanding the scope of this technology.
Keyphrases
- living cells
- mass spectrometry
- fluorescent probe
- quantum dots
- single molecule
- liquid chromatography
- small molecule
- dual energy
- high resolution
- high performance liquid chromatography
- capillary electrophoresis
- fluorescence imaging
- computed tomography
- electronic health record
- magnetic resonance
- positron emission tomography
- big data
- machine learning
- artificial intelligence
- data analysis
- pet ct