Casein Kinase 2 Mediates HIV- and Opioid-Induced Pathologic Phosphorylation of TAR DNA Binding Protein 43 in the Basal Ganglia.
Michael Ohene-NyakoSara R NassHope T RichardRobert LukandeMelanie R NicolMaryPeace McRaePamela E KnappKurt F HauserPublished in: ASN neuro (2023)
HIV/HIV-1 Tat and morphine independently increase pathologic phosphorylation of TAR DNA binding protein 43 in the striatum. HIV- and opioid-induced pathologic phosphorylation of TAR DNA binding protein 43 may involve enhanced CK2 activity and protein levels.
Keyphrases
- pain management
- binding protein
- antiretroviral therapy
- hiv positive
- hiv infected
- hiv testing
- chronic pain
- human immunodeficiency virus
- hepatitis c virus
- hiv aids
- protein kinase
- men who have sex with men
- circulating tumor
- neoadjuvant chemotherapy
- cell free
- single molecule
- high glucose
- south africa
- locally advanced
- endothelial cells