Aeration strategy at birth influences the physiological response to surfactant in preterm lambs.

David Gerald TingayAndrea TogoPrue M Pereira-FantiniMartijn MiedemaKaren E McCallElizabeth J PerkinsJessica ThomsonGeorgie DowseMagdy SourialRaffaele L DellacàPeter G DavisPeter Anderson Dargaville

Published in: Archives of disease in childhood. Fetal and neonatal edition (2019)

A DynPEEP strategy at birth may improve the response to early surfactant therapy, whereas rapid lung inflation with SI creates non-uniform aeration that appears to inhibit surfactant efficacy.

Keyphrases

gestational age
preterm birth
low birth weight
room temperature
pregnancy outcomes
pregnant women
mesenchymal stem cells
loop mediated isothermal amplification