Survival outcomes and toxicity profiles among patients with nonmetastatic nasopharyngeal carcinoma treated with intensity-modulated radiotherapy (IMRT) versus IMRT + carbon-ion radiotherapy: A propensity score-matched analysis.
Yujiao LiXiyin GuanXing XingChaosu HuPublished in: Head & neck (2024)
In this study, IMRT + CIRT was associated with significantly reduced acute toxicity burden compared with full course of IMRT, with excellent survival outcomes. Patients with persistent disease after treatment and treated with nodal boost had a worse outcome. More accurate assessments of IMRT + CIRT to primary nonmetastatic NPC patients will be imperative.
Keyphrases
- newly diagnosed
- early stage
- end stage renal disease
- locally advanced
- oxidative stress
- radiation therapy
- chronic kidney disease
- radiation induced
- liver failure
- squamous cell carcinoma
- neoadjuvant chemotherapy
- lymph node
- high resolution
- respiratory failure
- hepatitis b virus
- rectal cancer
- extracorporeal membrane oxygenation
- drug induced
- patient reported