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Impact of intra-tumoral immunity on predicting response and survival after neoadjuvant cisplatin-based chemotherapy in patients with muscle invasive bladder cancer.

Alberto Mendoza-ValderreyJane ChoeDaria M KesslerGianna JimenezXinmin LiSteven KolkerWarren AllenJennifer A LinehanPrzemyslaw W TwardowskiMaria Libera Ascierto
Published in: Cancer medicine (2024)
T cells and B cell infiltration are associated with improved response and long-term outcomes in patients with MIBC receiving NAC. These findings suggest that the impact of immune environment should be considered in determining the clinical outcome of MIBC patients treated with NAC.
Keyphrases
  • muscle invasive bladder cancer
  • transcription factor
  • locally advanced
  • rectal cancer
  • lymph node
  • squamous cell carcinoma
  • radiation therapy