Usefulness of combined NGS and QF-PCR analysis for product of conception karyotyping.

Takema KatoShunsuke MiyaiHideki SuzukiYuuri MuraseShiyo OtaHiroko YamauchiMichiko AmmaeTatsuya NakanoYoshiharu NakaokaTomoko InoueYoshiharu MorimotoAisaku FukudaTakafumi UtsunomiyaHaruki NishizawaHiroki Kurahashi

Published in: Reproductive medicine and biology (2022)

These data suggest that NGS-based sWGS, with the aid of QF-PCR, is a viable alternative karyotyping procedure that does not require cell culture. This method could also assist with genetic counseling for couples who undergoes embryo selection based on PGT-A data.

Keyphrases

electronic health record
big data
genome wide
minimally invasive
data analysis
gene expression
dna methylation
copy number
pregnant women
smoking cessation
hepatitis c virus
hiv testing
artificial intelligence
pregnancy outcomes
men who have sex with men
antiretroviral therapy