Sestrin2 knockout exacerbates high-fat diet induced metabolic disorders and complications in female mice.

Le ZhangChengxia KanJunfeng ShiHongyan QiuJingwen ZhangWenli DingLinfei XuKexin ZhangZhentao GuoNingning HouXiaodong Sun Fang Han

Published in: Nutrition & metabolism (2024)

Sesn2 KO exacerbates HFD-induced obesity and metabolic disorders in female mice. These findings underscore Sestrin2's novel role as a regulator of obesity in female mice.

Keyphrases

high fat diet induced
insulin resistance
high fat diet
metabolic syndrome
adipose tissue
skeletal muscle
high glucose
oxidative stress
transcription factor
risk factors
diabetic rats
weight loss
wild type
stress induced