QSM is an imaging biomarker for chronic glial activation in multiple sclerosis lesions.

Kelly McCabe GillenMayyan MubarakCalvin ParkGerald PonathShun ZhangAlexey DimovMaya Levine-RittermanSteven ToroWeiyuan HuangStephanie AmiciUlrike W KaunznerSusan A GauthierMireia Guerau-de-ArellanoYi WangThanh D NguyenDavid Pitt

Published in: Annals of clinical and translational neurology (2021)

A high QSM signal outlining the lesion rim but not punctate signal in the center is a biomarker for chronic inflammation in white matter lesions.

Keyphrases

white matter
multiple sclerosis
oxidative stress
high resolution
neuropathic pain
spinal cord
spinal cord injury