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QSM is an imaging biomarker for chronic glial activation in multiple sclerosis lesions.

Kelly McCabe GillenMayyan MubarakCalvin ParkGerald PonathShun ZhangAlexey DimovMaya Levine-RittermanSteven ToroWeiyuan HuangStephanie AmiciUlrike W KaunznerSusan A GauthierMireia Guerau-de-ArellanoYi WangThanh D NguyenDavid Pitt
Published in: Annals of clinical and translational neurology (2021)
A high QSM signal outlining the lesion rim but not punctate signal in the center is a biomarker for chronic inflammation in white matter lesions.
Keyphrases
  • white matter
  • multiple sclerosis
  • oxidative stress
  • high resolution
  • neuropathic pain
  • spinal cord
  • spinal cord injury