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A practical prognostic peripheral blood-based risk model for the evaluation of the likelihood of a response and survival of metastatic cancer patients treated with immune checkpoint inhibitors.

Satu TiainenVeera NurmelaTuomas SelanderPatrik TurunenSanna Pasonen-SeppänenTiia KettunenOuti KuittinenPäivi AuvinenAino L K Rönkä
Published in: BMC cancer (2023)
We propose a readily feasible, practical risk model consisted of six inflammation-related laboratory parameters as a tool for outcome prediction in metastatic cancer patients treated with ICIs. The risk model was strongly associated with the outcome of the patients in terms of all the evaluated indicators i.e., ORR, OS and PFS. Yet, further studies are needed to validate the risk model.
Keyphrases
  • squamous cell carcinoma
  • peripheral blood
  • small cell lung cancer
  • oxidative stress
  • ejection fraction
  • newly diagnosed
  • squamous cell
  • young adults
  • patient reported outcomes
  • childhood cancer
  • breast cancer risk