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DRP1 deficiency induces mitochondrial dysfunction and oxidative stress-mediated apoptosis during porcine oocyte maturation.

Haolin ZhangZhennan PanJiaqian JuChunhua XingXiaohan LiMengmeng ShanShao-Chen Sun
Published in: Journal of animal science and biotechnology (2020)
Taken together, our results indicate that DRP1 is essential for porcine oocyte maturation and that a DRP1 deficiency could induce mitochondrial dysfunction, oxidative stress, and apoptosis.
Keyphrases
  • oxidative stress
  • dna damage
  • diabetic rats
  • ischemia reperfusion injury
  • induced apoptosis
  • replacement therapy
  • endoplasmic reticulum stress
  • heat stress