DRP1 deficiency induces mitochondrial dysfunction and oxidative stress-mediated apoptosis during porcine oocyte maturation.
Haolin ZhangZhennan PanJiaqian JuChunhua XingXiaohan LiMengmeng ShanShao-Chen SunPublished in: Journal of animal science and biotechnology (2020)
Taken together, our results indicate that DRP1 is essential for porcine oocyte maturation and that a DRP1 deficiency could induce mitochondrial dysfunction, oxidative stress, and apoptosis.