Antiretroviral drug exposure and response in obese and morbidly obese people with HIV: a study combining modelling and Swiss HIV Cohort data.
Mattia BertonSara BettonteFelix StaderLaurent DecosterdPhilip E TarrFrançoise LivioMatthias CavassiniDominique L BraunKatharina KusejkoAnna HachfeldEnos BernasconiAlexandra CalmyPatrick SchmidManuel BattegayCatia MarzoliniPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2023)
The concentrations of ARVs are modestly reduced in obese with no negative impact on the virological response. Our data provide reassurance that standard dose of ARVs is suitable in obese PWH including those who gained substantial weight with some of the first-line ARVs.
Keyphrases
- weight loss
- hiv infected
- antiretroviral therapy
- obese patients
- adipose tissue
- hiv positive
- human immunodeficiency virus
- bariatric surgery
- metabolic syndrome
- hiv aids
- type diabetes
- hiv infected patients
- hepatitis c virus
- hiv testing
- electronic health record
- big data
- body mass index
- machine learning
- physical activity
- emergency department
- weight gain
- deep learning