Comparison of CK-IHC assay on serial frozen sections, the OSNA assay, and in combination for intraoperative evaluation of SLN metastases in breast cancer.

Hideo ShigematsuShinji OzakiDaisuke YasuiJunichi ZaitsuDaiki TaniyamaAkihisa SaitouKazuya KuraokaHiroyasu YamashiroKiyomi Taniyama

Published in: Breast cancer (Tokyo, Japan) (2017)

The CK-IHC assay and the OSNA assay have compatible diagnostic abilities in intraoperative evaluations for SLN metastases. The low incidence of false negative results with limited disease burden suggests that both assays can be reliable techniques for intraoperative diagnoses of SLN metastases in breast cancer patients.

Keyphrases

high throughput
patients undergoing
risk factors
protein kinase
single cell
early stage
lymph node
clinical evaluation