Clinical significance of PET-CT coronary flow reserve in diagnosis of non-obstructive coronary artery disease.
Henry Anselmo MayalaKhamis Hassan BakariFabian Pius MghangaWang ZhaoHuiPublished in: BMC research notes (2018)
In our study 92% were between 41 and 60 years. 83% were males and 17% females, more patients had hypertension about 50%, few had diabetes mellitus about 16%, while those with both hypertension and diabetes mellitus were 17%. About 83% had ST segment and T wave changes on ECG. All patients and controls had normal coronaries on coronary angiography TIMI 3 flow. On further investigation by Positron emission tomography/CT we found out 58% had abnormal CFR and 42% had normal coronary flow reserve. Our findings indicate PET/CT coronary flow reserve concept provides a platform for the diagnosis of non-obstructive coronary artery disease in patients with signs and symptoms of ischemia without angiographic obstructive CAD.
Keyphrases
- coronary artery disease
- pet ct
- positron emission tomography
- computed tomography
- blood pressure
- ejection fraction
- newly diagnosed
- cardiovascular events
- percutaneous coronary intervention
- coronary artery bypass grafting
- type diabetes
- magnetic resonance imaging
- cardiovascular disease
- metabolic syndrome
- physical activity
- patient reported outcomes
- skeletal muscle
- insulin resistance
- single cell