Kif1a and intact microtubules maintain synaptic-vesicle populations at ribbon synapses in zebrafish hair cells.

Sandeep DavidKatherine PinterKeziah-Khue NguyenDavid S LeeZhengchang LeiYuliya SokolovaLavinia Sheets Katie S Kindt

Published in: bioRxiv : the preprint server for biology (2024)

Kif1a mRNAs are present in zebrafish hair cellsLoss of Kif1a disrupts the enrichment of synaptic vesicles at ribbon synapsesDisruption of microtubules depletes synaptic vesicles at ribbon synapsesKif1a mutants have impaired ribbon-synapse and sensory-system function.

Keyphrases

prefrontal cortex
induced apoptosis
cell cycle arrest
oxidative stress
cell proliferation
genetic diversity
wild type