Defining a prognostic score based on O6-methylguanine-DNA methyltransferase cut-off methylation level determined by pyrosequencing in patients with glioblastoma multiforme.

Elisa De CarloLorenzo GerratanaGiovanna De MaglioVanessa BuoroFrancesco CortiulaLorena GurrieriMiriam IsolaGianpiero FasolaFabio PuglisiStefano PizzolittoSimona Rizzato

Published in: Journal of neuro-oncology (2018)

The present manuscript explored a novel scoring system capable to take into consideration the methylation status of each single CpGi, capable to better predict prognosis in GBM patients.

Keyphrases

end stage renal disease
newly diagnosed
dna methylation
ejection fraction
genome wide
chronic kidney disease
gene expression
single molecule
nucleic acid
patient reported