Expanding the spectrum of low-grade sinonasal adenocarcinoma with biphasic seromucinous differentiation and activating HRAS/AKT1 mutations.
Viktoria S HadnagyMeike KörnerMatthias RösslePatrick DubachGunther PabstAlexandra KotulovaStefan WederRobert SeifertElisabeth J RushingDavid HolzmannMartin HüllnerSandra N FreibergerNiels J RuppPublished in: Histopathology (2024)
This study further corroborates a distinct biphasic low-grade neoplasm of the sinonasal tract with seromucinous differentiation. Although morphological and molecular features overlap with salivary gland epithelial-myoepithelial carcinoma, several arguments favour categorising these tumours within the spectrum of LGSNAC.