Transplantation of Hypoxic-Preconditioned Bone Mesenchymal Stem Cells Retards Intervertebral Disc Degeneration via Enhancing Implanted Cell Survival and Migration in Rats.

Weiheng WangYang WangGuoying DengJun MaXiaodong HuangJiangming YuYanhai XiXiaojian Ye

Published in: Stem cells international (2018)

HP could significantly enhance the capacity of BMSCs to repair DDD by increasing the survival and migration of implanted cells and increasing matrix protein expression.

Keyphrases

mesenchymal stem cells
induced apoptosis
cell cycle arrest
umbilical cord
bone mineral density
cell therapy
bone marrow
endoplasmic reticulum stress
oxidative stress
stem cells
free survival
soft tissue
pi k akt