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Maternal intrahepatic cholestasis of pregnancy and neurodevelopmental conditions in offspring: A population-based cohort study of 2 million Swedish children.

Shuyun ChenViktor H AhlqvistHugo SjöqvistOlof StephanssonCecilia MagnussonChristina DalmanHåkan KarlssonBrian K LeeRenee M Gardner
Published in: PLoS medicine (2024)
In this study, we observed that exposure to ICP during gestation is associated with an increased likelihood of neurodevelopmental conditions in offspring, particularly in cases of early-onset ICP. Further studies are warranted to better understand the role of early-ICP in offspring neurodevelopment.
Keyphrases
  • early onset
  • high fat diet
  • late onset
  • pregnancy outcomes
  • young adults
  • preterm infants
  • type diabetes
  • insulin resistance
  • congenital heart disease
  • metabolic syndrome
  • weight loss