Clinical, molecular, metabolic, and immune features associated with oxidative phosphorylation in melanoma brain metastases.

Grant M FischerRenato A Guerrieri Qianghua Hu Aron Y JoonSwaminathan KumarLauren E HayduJennifer L McQuadeVashisht Gopal Y NBarbara KnightonWanleng DengCourtney W Hudgens Alexander J F Lazar Michael T Tetzlaff Michael A Davies

Published in: Neuro-oncology advances (2021)

OXPHOS is associated with distinct clinical, molecular, metabolic, and immune phenotypes in MBMs. These associations suggest rational therapeutic strategies for further testing to improve outcomes in MBM patients.

Keyphrases

brain metastases
end stage renal disease
small cell lung cancer
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
type diabetes
metabolic syndrome
patient reported outcomes
weight loss
patient reported
glycemic control