High sugar and butter (HSB) diet induces obesity and metabolic syndrome with decrease in regulatory T cells in adipose tissue of mice.

Tatiani Uceli MaioliJuliana Lauar GonçalvesMariana Camila Gonçalves MirandaVinícius Dantas MartinsLaila Sampaio HortaThais Garcias MoreiraAna Lucia Brunialti GodardAndrezza Fernanda SantiagoAna Maria Caetano Faria

Published in: Inflammation research : official journal of the European Histamine Research Society ... [et al.] (2015)

Therefore, HSB represents a novel model of obesity-inducing diet that was efficient in triggering alterations compatible with metabolic syndrome as well as impairment in immune regulatory parameters.

Keyphrases

metabolic syndrome
regulatory t cells
insulin resistance
high fat diet induced
weight loss
adipose tissue
physical activity
uric acid
dendritic cells
high fat diet
cardiovascular risk factors
type diabetes
transcription factor
skeletal muscle
cardiovascular disease