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BET Bromodomain Inhibition Potentiates Ocular Melanoma Therapy by Inducing Cell Cycle Arrest.
Xingyu Chen
Rui Huang
Zhe Zhang
Xin Song
Jianfeng Shen
Qiang Wu
Published in:
Investigative ophthalmology & visual science (2024)
JQ-1 may act downstream of BRD4 and suppress ocular melanoma growth by inducing G1 cell cycle arrest.
Keyphrases
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cell cycle arrest
cell death
pi k akt
skin cancer
optic nerve
signaling pathway
basal cell carcinoma
cell proliferation
stem cells
mesenchymal stem cells
bone marrow
replacement therapy