Novel murine model of congenital diabetes: The insulin hyposecretion mouse.

Kenta NakanoRieko Yanobu-TakanashiYuki TakahashiHayato SasakiYukiko ShimizuTadashi OkamuraNobuya Sasaki

Published in: Journal of diabetes investigation (2018)

The ihs mouse provides a novel murine model of congenital diabetes that shows insulin secretion failure. This model allows not only an analysis of the progression of diabetes, but also the identification of unknown genes involved in insulin secretion.

Keyphrases

type diabetes
glycemic control
cardiovascular disease
insulin resistance
metabolic syndrome
skeletal muscle
adipose tissue