Risk of hepato-pancreato-biliary cancer is increased by primary sclerosing cholangitis in patients with inflammatory bowel disease: A population-based cohort study.
Jingru YuErle RefsumLise M HelsingenTrine FolseraasAlexander PlonerPaulina WieszczyIshita BaruaHenriette C JodalEspen MelumMagnus LøbergJohannes BlomMichael BretthauerHans-Olov AdamiMette KalagerWeimin YePublished in: United European gastroenterology journal (2022)
The dramatically increased risks of hepato-pancreato-biliary cancers in PSC-IBD patients support periodic surveillance for these malignancies. While much lower, the excess relative risks in non-PSC-IBD patients were not trivial compared to non-IBD related risk factors.