Pancreatic Cancer Surveillance in Carriers of a Germline CDKN2A Pathogenic Variant: Yield and Outcomes of a 20-Year Prospective Follow-Up.

Derk C F Klatte Bas BoekestijnMartin N J M WasserShirin Feshtali ShahbaziIsaura S IbrahimJ Sven D MieogSaskia A C LuelmoHans MorreauThomas P PotjerAkin IndersonJurjen J BoonstraFriedo W DekkerHans F A VasenJeanin E van Hooft Bert A BonsingMonique E van Leerdam

Published in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2022)

. This provides evidence that surveillance in such a high-risk population leads to detection of early-stage PDAC with improved resectability and survival.

Keyphrases

early stage
public health
sentinel lymph node
squamous cell carcinoma
type diabetes
metabolic syndrome
dna damage
weight loss
neoadjuvant chemotherapy