Diagnostic delay and outcome in immunocompetent patients with primary central nervous system lymphoma in Spain: a multicentric study.
Roser VelascoS MercadalN VidalM AlañáM I BarcelóM J Ibáñez-JuliáS BobilloR Caldú AgudE García MolinaP MartínezP CacabelosA MuntañolaG García-CatalánJ M SanchoI CamroT LadoM E ErroL Gómez-VicenteA SalarA C CaballeroM Solé-RodríguezJ Gállego Pérez-LarrayaN HuertasJ EstelaM BarónN Barbero-BordalloM EncuentraI DlouhyJ BrunaF Grausnull nullPublished in: Journal of neuro-oncology (2020)
Corticosteroids withdrawal before surgery does not decrease the risk of a negative biopsy but delays diagnosis. In this community-based study, only 73.4% of patients could receive HD-MTX-based chemotherapy and OS remains poor, particularly in elderly patients ≥ 70 years.