Mechanosensors, as the core component of a proprioceptive system, can detect many types of mechanical signals in their surroundings, such as force signals, displacement signals, and vibration signals. It is understandable that the development of an all-new mechanosensory structure that can be widely used is highly desirable. This is because it can markedly improve the detection performance of mechanosensors. Coincidentally, in nature, optimized microscale trigger hairs of Venus flytrap are ingeniously used as a mechanosensory structure. These trigger hairs are utilized for tactile mechanosensilla to efficiently detect external mechanical stimuli. Biological trigger hair-based mechanosensilla offer an all-new bio-inspired strategy. This strategy utilizes the notch structure and variable stiffness to enhance the perceptual performance of mechanosensors. In this study, the structure-performance-application coupling relationship of trigger hair-based mechanosensors is explored through experiment and analysis. An artificial trigger hair-based mechanosensor is developed by mimicking the deformation properties of the Venus flytrap trigger hair. This bio-inspired mechanosensor shows excellent performance in terms of mechanical stability, response time, and sensitivity to mechanical signals.