Analysis by proteomics reveals unique circulatory proteins in idiopathic pulmonary fibrosis.
Yuben P MoodleyTamera J CorteBrian G OliverIan N GlaspoleAndreja LivkJason ItoKirsten PetersRichard LipscombeTammy CaseyDino B A TanPublished in: Respirology (Carlton, Vic.) (2019)
This study further validates the combinational use of non-targeted discovery proteomics (iTRAQ) with targeted quantitation by mass spectrometry (MRM) of soluble biomarkers to identify potentially important molecules and pathways for pulmonary diseases such as IPF.
Keyphrases
- idiopathic pulmonary fibrosis
- mass spectrometry
- liquid chromatography
- interstitial lung disease
- high performance liquid chromatography
- cancer therapy
- gas chromatography
- capillary electrophoresis
- high resolution
- pulmonary hypertension
- tandem mass spectrometry
- ms ms
- extracorporeal membrane oxygenation
- label free
- rheumatoid arthritis
- liquid chromatography tandem mass spectrometry
- simultaneous determination
- systemic sclerosis