Resolvin D2-GPR18 Signaling on Myeloid Cells Limits Plaque Necrosis.
Masharh LipscombSean WalisMichael MarinelloHebe Agustina MenaMatthew SpiteGabrielle FredmanPublished in: bioRxiv : the preprint server for biology (2023)
These results are the first to suggest a causative role for endogenous RvD2 signaling on myeloid cells in limiting plaque necrosis. Moreover, these results provide a mechanistic basis for RvD2 as a therapy limiting plaque necrosis.