EIF5A regulates proliferation and chemoresistance in pancreatic cancer through the sHH signalling pathway.

Zheng WangJie JiangTao QinYing XiaoLiang Han

Published in: Journal of cellular and molecular medicine (2019)

Taken together, our results revealed that EIF5A regulated the proliferation of PC through the sHH signalling pathway and decreased the Gem sensitivity in PC, which provided a novel therapeutic strategy for PC patients.

Keyphrases

end stage renal disease
signaling pathway
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
transcription factor
cancer stem cells