In vitro and in silico anti-dengue activity of compounds obtained from Psidium guajava through bioprospecting.
Andrea Isabel Trujillo-CorreaDiana Carolina Quintero-GilFredyc Diaz-CastilloWinston QuiñonesSara M RobledoDamião Pergentino de SousaPublished in: BMC complementary and alternative medicine (2019)
Even though bioprospecting has recently been replaced by more targeted tools for identifying compounds with pharmacological potential, our results show it is still useful for this purpose. Additionally, combining in vitro and in silico evaluations allowed us to identify promising antivirals as well as their possible mechanisms of action.