Hypoxemia during rapid eye movement sleep mediates memory impairment in older adults at risk for dementia via CA1 hippocampal volume loss.

Aaron Kin Fu LamAngela L D'RozarioJake R PalmerAndrew McKinnonMarshall R DaltonNicole EspinosaLoren MowszowskiCraig L PhillipsRonald R GrunsteinSharon L Naismith

Published in: European journal of neurology (2024)

Hypoxemia during REM sleep may impair memory in people at risk for dementia by reducing CA1 hippocampal volume. Research is needed to explore whether interventions targeting REM sleep hypoxemia are protective against memory decline.

Keyphrases

physical activity
working memory
sleep quality
mild cognitive impairment
cognitive impairment
cerebral ischemia
protein kinase
depressive symptoms
drug delivery