Iron-Catalyzed Regio- and Stereoselective Hydrosilylation of 1,3-Enynes To Access 1,3-Dienylsilanes.

A regio- and stereoselective hydrosilylation of 1,3-enynes with primary and secondary silanes to access 1,3-dienylsilanes is accomplished by employing an iron precatalyst bearing iminopyridine-oxazoline (IPO) ligand. The hydrosilylation proceeds via syn-addition of a Si-H bond to the alkyne group of 1,3-enynes, incorporating the silyl group at the site proximal to the alkene. The reaction features mild conditions, broad substrate scope, and good functional group tolerance. The synthetic utility was demonstrated by gram-scale reactions and further transformations.